Standard Treatment As with the other types, the standard treatment for these sarcomas usually includes a hysterectomy , removal of the tubes and ovaries on both sides, selective pelvic and aortic node sampling and abdominal cytologic washings.
Early-stage disease can also be treated by a radical hysterectomy, removal of the pelvic lymph nodes and sampling of the aortic nodes, removal of the tubes and ovaries and abdominal cytologic washings.
Postoperative radiation therapy to the pelvis (4,500 to 5,000 cGy given in divided doses, five days a week for five weeks) is often given to decrease the chance of a pelvic recurrence . The frequency of recurrence depends primarily on the depth of uterine invasion.
Since these tumors frequently contain progesterone and/or estrogen receptors, hormone therapy with progestins or the antiestrogen tamoxifen is often given.
Investigational
• Various types and doses of progestins and antiestrogens are being studied.
